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D L Kolesnik Selected Research

Dichloroacetic Acid

1/2020Tumor microenvironment changes tumor cell sensitivity to action of energy metabolism modifiers.
3/2019Time-dependent cytotoxicity of dichloroacetate and metformin against Lewis lung carcinoma.
1/2019Metformin enhances antitumor action of sodium dichloroacetate against glioma C6.
10/2018Influence of metformin, sodium dichloroacetate and their combination on the hematological and biochemical blood parameters of rats with gliomas C6.
6/2016Effectiveness of sodium dichloroacetate against glioma C6 depends on administration schedule and dosage.

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D L Kolesnik Research Topics

Disease

15Neoplasms (Cancer)
01/2021 - 09/2007
10Lewis Lung Carcinoma
04/2021 - 09/2007
5Glioma (Gliomas)
01/2019 - 12/2014
4Neoplasm Metastasis (Metastasis)
01/2020 - 09/2007
2Hypoxia (Hypoxemia)
06/2016 - 12/2014
1Circulating Neoplastic Cells
01/2020
1Diabetes Mellitus
12/2017
1Lactic Acidosis
07/2017
1Acidosis
07/2017
1Paraneoplastic Syndromes (Paraneoplastic Syndrome)
12/2015
1Carcinoma (Carcinomatosis)
09/2015
1Body Weight (Weight, Body)
06/2015
1Hyperoxia
12/2014
1Necrosis
12/2014
1Malnutrition (Nutritional Deficiencies)
12/2008

Drug/Important Bio-Agent (IBA)

8Lactic Acid (Lactate)FDA LinkGeneric
01/2020 - 12/2014
6Metformin (Glucophage)FDA LinkGeneric
01/2020 - 12/2017
6Glucose (Dextrose)FDA LinkGeneric
01/2020 - 12/2008
5Dichloroacetic AcidIBA
01/2020 - 06/2016
4Oxygen (Dioxygen)IBA
03/2019 - 12/2014
3L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
01/2021 - 12/2014
3Cytostatic AgentsIBA
01/2020 - 12/2014
3Heme (Haem)IBA
01/2020 - 03/2014
3IronIBA
01/2020 - 03/2014
3Reactive Oxygen Species (Oxygen Radicals)IBA
09/2016 - 03/2014
3EnzymesIBA
06/2015 - 09/2007
2Adenosine Triphosphate (ATP)IBA
01/2019 - 06/2016
2Biological ProductsIBA
06/2016 - 03/2014
2Trypan BlueFDA Link
06/2015 - 12/2014
1SuspensionsIBA
04/2021
1tungsten sulfideIBA
04/2021
1SodiumIBA
01/2021
1Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2021
1ArginaseIBA
01/2021
1Hemeproteins (Heme Protein)IBA
01/2020
1Antineoplastic Agents (Antineoplastics)IBA
01/2020
1SulfurIBA
01/2020
1Hypoglycemic Agents (Hypoglycemics)IBA
12/2017
1Pharmaceutical PreparationsIBA
12/2017
1Fluorescein-5-isothiocyanate (FITC)IBA
09/2016
1Deoxyglucose (2 Deoxy D glucose)IBA
09/2016
1CarbonIBA
12/2015
1Angiogenesis InhibitorsIBA
09/2015
1AconitineIBA
09/2015
1Proteins (Proteins, Gene)FDA Link
06/2015
1Pyruvate Dehydrogenase Acetyl-Transferring KinaseIBA
12/2014
1PlasticsIBA
12/2014
1Coloring Agents (Dyes)IBA
12/2014
1Superoxide DismutaseIBA
03/2014
1AntioxidantsIBA
03/2014
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
09/2007
1ImmunosorbentsIBA
09/2007
1Cisplatin (Platino)FDA LinkGeneric
09/2007

Therapy/Procedure

5Therapeutics
01/2020 - 12/2015
4Cell Transplantation
10/2018 - 12/2015
2Transplantation
01/2021 - 06/2015
1Enterosorption
12/2015